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Star Prestige Daily

What drugs interact with Humira

Author

Amelia Brooks

Published Jul 03, 2026

You should not take HUMIRA with ORENCIA® (abatacept), KINERET® (anakinra), REMICADE® (infliximab), ENBREL® (etanercept), CIMZIA® (certolizumab pegol), or SIMPONI® (golimumab). Tell your doctor if you have ever used RITUXAN® (rituximab), IMURAN® (azathioprine), or PURINETHOL® (mercaptopurine, 6-MP).

What medications should not be taken with Humira?

You should not take HUMIRA with ORENCIA® (abatacept), KINERET® (anakinra), REMICADE® (infliximab), ENBREL® (etanercept), CIMZIA® (certolizumab pegol), or SIMPONI® (golimumab). Tell your doctor if you have ever used RITUXAN® (rituximab), IMURAN® (azathioprine), or PURINETHOL® (mercaptopurine, 6-MP).

What drugs does adalimumab interact with?

  • Adalimumab has serious interactions with at least 67 different drugs.
  • Moderate interactions of adalimumab include: astragalus. belatacept. denosumab. echinacea. fingolimod. hydroxyurea. …
  • Mild interactions of adalimumab include: cat’s claw. methotrexate.

Does Humira interact with anything?

Do not start, stop, or change the dosage of any medicines without your doctor’s approval. Some products that may interact with this drug include: other TNF blockers (such as etanercept, infliximab), other drugs that weaken the immune system (such as abatacept, anakinra).

Can I take Tylenol while on Humira?

No interactions were found between Humira and Tylenol. This does not necessarily mean no interactions exist. Always consult your healthcare provider.

Are Humira patients immunocompromised?

AbbVie has not studied the use of HUMIRA in patients with COVID-19. At this time, the safety and efficacy of the authorized COVID-19 vaccines have not been established in immunocompromised persons, persons with autoimmune conditions or persons who take immunosuppressive medications or therapies1 such as HUMIRA.

Why can't I drink alcohol while on Humira?

Drinking alcohol and taking certain medicines can place extra demands on the liver, causing liver damage. However, the liver does not break down Humira. This mean, it is less likely that drinking alcohol and using Humira will cause damage compared with other medications, such as acetaminophen.

Can you take naproxen while on Humira?

No interactions were found between Aleve and Humira. This does not necessarily mean no interactions exist. Always consult your healthcare provider.

Can I take ibuprofen while on Humira?

No interactions were found between Humira and ibuprofen. This does not necessarily mean no interactions exist. Always consult your healthcare provider.

Should I take folic acid with Humira?

Interactions between your drugs No interactions were found between folic acid and Humira. This does not necessarily mean no interactions exist. Always consult your healthcare provider.

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Does Humira affect your eyes?

Although Humira is not known to specifically cause eye-related side effects, it may cause other side effects that can affect your eyes. For example, Humira can cause nervous system problems. Symptoms of some nervous system problems may include changes in your vision. Humira can also cause liver damage.

Can you take hydroxychloroquine with Humira?

Interactions between your drugs Using hydroxychloroquine together with adalimumab may increase the risk of nerve damage, which is a potential side effect of both medications. Talk to your doctor if you have any questions or concerns.

Can you have a flare up while on Humira?

Inflammatory bowel disease patients taking the biologicals Humira or Cimzia (certolizumab) are at significant risk of flare-ups if they delay refilling their prescriptions for more than two days out of two weeks, a study found.

Can you take vitamins with Humira?

Interactions between your drugs No interactions were found between Humira and Vitamin D3. This does not necessarily mean no interactions exist. Always consult your healthcare provider.

Can I take nsaids with Humira?

Humira can be taken together with other medicines, such as methotrexate, and other disease-modifying anti-rheumatic agents (for example, sulfasalazine, hydroxychloroquine, leflunomide and injectable gold preparations), steroids or pain medications including non- steroidal anti-inflammatory drugs (NSAIDS) such as …

Does Humira affect your teeth?

Although rare, it is possible for Humira and methotrexate to cause the destruction of bone tissue, particularly in the jaw and teeth.

Does Humira make you gain weight?

Weight gain wasn’t reported as a side effect in clinical studies of Humira. However, weight gain has been reported with the use of other medications called tumor necrosis factor (TNF) blockers. Humira is a type of TNF blocker.

Can Humira affect hair?

Biologics: In rare cases, biologics such as etanercept (Enbrel) or adalimumab (Humira) have hair loss side effects. It’s not known exactly why these drugs affect hair growth, but it’s suspected it’s because they change the balance of messenger molecules known as “cytokines” in the body.

Does Humira cause belly fat?

After your inflammation and pain are controlled with Humira, you may feel better and your appetite may return, leading to weight gain. This typically would happen slowly over time.

What happens if I get sick while on Humira?

You might get infections more easily while you are receiving HUMIRA treatment. These infections may be serious and include tuberculosis, infections caused by viruses, fungi or bacteria, or other opportunistic infections and sepsis that may, in rare cases, be life threatening.

What is the Humira hangover?

Since Keegan, my husband with AS, began taking Humira over 2 years ago, he’s always talked about a “Humira hangover.” He’d describe it as a small period of time where his AS symptoms would peak from taking Humira. It’d knock him out for almost an entire day sometimes.

Has Humira killed anyone?

Humira was linked to 169,000 reported serious adverse events and 13,000 reports of deaths, followed by Enbrel with 135,000 serious events and 8,000 deaths.

Does Humira make you tired?

However, this medication can also trigger fatigue by interfering with the body’s normal metabolism. Other medications, such as etanercept (Enbrel), adalimumab (Humira), and infliximab (Remicade) have been reported to reduce fatigue, but some experts suspect this reduction may be limited and not permanent.

Is Humira an Nsaid?

Adalimumab, which is sold under the brand name Humira by AbbVie, is a type of anti-inflammatory known as an anti-tumour necrosis factor (anti-TNF) drug.

Does Humira cause extreme fatigue?

Serious side effects of Humira Swollen glands, tiredness, fever, chills, night sweats, loss of appetite, involuntary weight loss, unexplained skin bumps, easy bruising or bleeding, or other common signs of cancer.

What should I take with Humira?

HUMIRA is a prescription medicine used to reduce signs and symptoms, and to achieve and maintain clinical remission in adults with moderate to severe Crohn’s disease who have not responded well to certain other medications.

Does Humira stop arthritis?

HUMIRA Use HUMIRA is a prescription medicine used alone, with methotrexate, or with certain other medicines to reduce the signs and symptoms of moderate to severe rheumatoid arthritis in adults, may prevent further damage to your bones and joints, and may help your ability to perform daily activities.

Can I take Humira and Celebrex together?

No interactions were found between Celebrex and Humira. This does not necessarily mean no interactions exist. Always consult your healthcare provider.

Should I take Humira in the morning or at night?

Some people find it helpful to inject HUMIRA in the morning or at bedtime. However, once you find a time that you prefer, using the medicine at a consistent time can help you remember to take it. It’s also a good idea to mark your calendar with the dates of your treatment as this may help you remember when to use it.

Where is the best place to inject Humira?

You can give yourself Humira injections in the abdomen or front thigh. The most common injection site is the abdomen. The abdomen is also the most recommended site because it is the least painful.

Does Humira affect your sleep?

Treatment with Humira (adalimumab) increases work productivity, reduces sleep problems, and eases disease activity in people with ankylosing spondylitis (AS) and related diseases, a new real-world study indicates.